Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15128610 | 0.92 | TSHR (0.45) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL15715715 | 0.91 | LTA4H (0.44) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL19040816 | 0.89 | LTA4H (0.43) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL19040904 | 0.89 | LTA4H (0.43) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL20667097 | 0.89 | LTA4H (0.43) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL10169910 | 0.86 | TSHR (0.36) | TSHRALDH1A1RECQLHPGDTDP1 | |
| SCHEMBL838146 | 0.85 | TSHR (0.36) | TSHRALDH1A1RECQLTDP1L3MBTL1 | |
| SCHEMBL19886841 | 0.85 | LTA4H (0.44) | TSHRALDH1A1RECQLLTA4HHPGD | |
| SCHEMBL14790917 | 0.83 | LMNA (0.39) | TSHRALDH1A1TDP1L3MBTL1 | |
| SCHEMBL18323388 | 0.82 | NCF1 (0.38) | ALDH1A1LTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360759-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | SYNGENE INTERNATIONAL LIMITED (IN) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360759-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | TSHR 554/4885ALDH1A1 3382/4885RECQL 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.