Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10170664 | 0.81 | AR (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8514221 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL30963650 | 0.78 | KDM4E (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL1142900 | 0.78 | KDM4E (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL10170655 | 0.77 | KDM4E (0.49) | ALDH1A1SMN1; SMN2L3MBTL1KDM5A | |
| Hydrochloric Acid SCHEMBL8514225 | 0.76 | KDM4E (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL112846 | 0.76 | GAA (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL30242159 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL333768 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL24983917 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168668-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-05-01 | — | — | US | disclosed |
| US-20100286202-A1 | New Compounds | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286202-A1 | New Compounds | REN, PCSK9, FURIN | ALDH1A1 1484/4885CYP1A2 533/4885CYP2C9 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.