Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242159 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14855312 | 0.78 | CCR1 (0.36) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL565602 | 0.77 | ALDH1A1 (0.43) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30376853 | 0.77 | ALDH1A1 (0.43) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31253097 | 0.77 | HRH4 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1641172 | 0.77 | HRH4 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30164142 | 0.77 | MBOAT4 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2394294 | 0.77 | MBOAT4 (0.45) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20110653 | 0.77 | GRM5 (0.36) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21927209 | 0.76 | HRH4 (0.44) | ALDH1A1NPSR1HRH4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751448-A | Preparation method of 3-iodo-6-methyl-1H-pyrazolo [3,4-b ] pyridine | 上海医药集团(本溪)北方药业有限公司 | 2025-04-04 | — | — | CN | claimed |
| EP-3162796-B1 | METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID | AGRO KANESHO CO LTD (JP) | 2021-06-09 | — | — | EP | claimed |
| CN-106458908-B | The manufacturing method of 2- amino -6- methylnicotinic acids | 阿格罗－金正株式会社 | 2018-11-06 | — | — | CN | claimed |
| US-9902697-B2 | Method for producing 2-amino-6-methylnicotinic acid | AGRO-KANESHO CO., LTD. (JP) | 2018-02-27 | — | — | US | claimed |
| US-9714223-B2 | — | — | 2017-07-25 | — | — | US | claimed |
| US-20170129858-A1 | METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID | AGRO-KANESHO CO., LTD. (JP) | 2017-05-11 | — | — | US | claimed |
| EP-3162796-A1 | METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID | Agro-Kanesho Co., Ltd. (JP) | 2017-05-03 | — | — | EP | claimed |
| US-20130252953-A1 | Targeting Human Thymidylate Kinase Induces DNA Repair Toxicity in Malignant Tumor Cells | NATIONAL YANG-MING UNIVERSITY (TW) | 2013-09-26 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| CN-122010928-A | PCSK9 inhibitor and application thereof | 江苏柯菲平医药股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12508268-B2 | Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2025-12-30 | — | — | US | disclosed |
| EP-4637748-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-0243868-A2 | Pyridylthio-acylanilides | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |
| CN-85108698-A | The preparation method and the application thereof of N-substituted aziridine-2-carboxylic acid | — | 1986-07-23 | — | — | CN | disclosed |
| EP-0104876-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-04-04 | — | — | EP | disclosed |
| US-4350817-A | 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| US-4324893-A | 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252953-A1 | Targeting Human Thymidylate Kinase Induces DNA Repair Toxicity in Malignant Tumor Cells | DTYMK, TYMP, DCK | ALDH1A1 1837/4885NPSR1 4768/4885CYP1A2 4537/4885 |
| US-12508268-B2 | Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy | IDO1, IDO2, TDO2 | ALDH1A1 732/4885NPSR1 223/4885CYP1A2 845/4885 |
| US-20170129858-A1 | METHOD FOR PRODUCING 2-AMINO-6-METHYLNICOTINIC ACID | MAT2A, AADAT, AMPD2 | ALDH1A1 919/4885NPSR1 2737/4885CYP1A2 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.