Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867798 | 0.80 | RARA (0.43) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL566401 | 0.79 | RARB (0.42) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL13380473 | 0.79 | S1PR3 (0.36) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL566419 | 0.72 | RARB (0.51) | S1PR3CYP3A4S1PR1TNNC1SGPL1 | |
| Hydrochloric Acid SCHEMBL566817 | 0.71 | RARB (0.50) | CYP3A4S1PR1ALOX15 | |
| SCHEMBL10139270 | 0.68 | RARA (0.45) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL10139272 | 0.67 | S1PR1 (0.39) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL10171069 | 0.67 | S1PR1 (0.57) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL566087 | 0.67 | S1PR1 (0.39) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL2867806 | 0.66 | NUDT1 (0.40) | S1PR3CYP3A4CYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | S1PR3 3/4885CYP3A4 4526/4885CYP2C8 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.