Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NEK7 | Q8TDX7 | 7/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172171 | 0.96 | HDAC4 (0.47) | HDAC4GPR119NEK7PDGFRBKDR | |
| SCHEMBL356206 | 0.96 | HDAC4 (0.47) | HDAC4GPR119NEK7PDGFRBKDR | |
| SCHEMBL356205 | 0.96 | HDAC4 (0.47) | HDAC4GPR119NEK7PDGFRBKDR | |
| SCHEMBL10171900 | 0.94 | HDAC4 (0.42) | HDAC4GPR119ERBB2HDAC6NEK7 | |
| SCHEMBL10171849 | 0.93 | GPR119 (0.40) | HDAC4GPR119ERBB2HDAC6NEK7 | |
| SCHEMBL10172638 | 0.89 | PDGFRB (0.39) | GPR119ERBB2NEK7PDGFRBKDR | |
| SCHEMBL10172671 | 0.88 | GPR119 (0.43) | GPR119NEK7BRAFCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL355012 | 0.88 | GPR119 (0.43) | GPR119NEK7BRAFCYP3A4CYP2C9 | |
| SCHEMBL354254 | 0.86 | HDAC4 (0.45) | HDAC4GPR119ERBB2NEK7PDGFRB | |
| SCHEMBL10171852 | 0.86 | GPR119 (0.53) | HDAC4GPR119ERBB2NEK7BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | HDAC4 2551/4885GPR119 1/4885ERBB2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.