SCHEMBL10172789

SCHEMBL10172789

CC(CO)OCCCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.44
TSHR P16473 5/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42
GPR84 Q9NQS5 8/20 0.41
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 2/20 0.41
AKR1B1 P15121 1/20 0.41
PPARG P37231 7/20 0.40
PPARD Q03181 7/20 0.40
PPARA Q07869 7/20 0.40
HDAC11 Q96DB2 5/20 0.40
PTPN1 P18031 3/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL28315137 0.85 AKR1B1 (0.46) ALDH1A1LMNATSHRGPR84FFAR1
SCHEMBL6903572 0.84 ALDH1A1 (0.50) ALDH1A1LMNATSHRNFKB1PMP22
SCHEMBL8400588 0.84 ALDH1A1 (0.50) ALDH1A1LMNATSHRNFKB1PMP22
SCHEMBL15264553 0.82 TSHR (0.37) ALDH1A1TSHRTDP1
SCHEMBL8400587 0.82 ALDH1A1 (0.53) ALDH1A1LMNATSHRNFKB1PMP22
SCHEMBL14018898 0.81 ALDH1A1 (0.56) ALDH1A1LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL4595421 0.81 LMNA (0.41) ALDH1A1LMNATSHRNFKB1PMP22
SCHEMBL10172791 0.81 TSHR (0.50) ALDH1A1LMNATSHRPPARGKMT2A
Azelaic Acid SCHEMBL8503430 0.79 TSHR (0.43) ALDH1A1LMNATSHRNFKB1PMP22
SCHEMBL5903338 0.79 ALDH1A1 (0.59) ALDH1A1LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124800-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2012-02-28 US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 ALDH1A1 2028/4885LMNA 3060/4885TSHR 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.