Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172812 | 0.96 | ALDH1A1 (0.51) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL10172880 | 0.91 | ALDH1A1 (0.53) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL10067116 | 0.86 | ALDH1A1 (0.44) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL10172810 | 0.83 | NPSR1 (0.50) | ALDH1A1NPSR1GAAL3MBTL1LMNA | |
| SCHEMBL20008913 | 0.82 | NPSR1 (0.57) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL10172817 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL10172809 | 0.82 | NPSR1 (0.52) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL7459150 | 0.81 | NPSR1 (0.57) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL18232630 | 0.80 | ALDH1A1 (0.46) | ALDH1A1NPSR1ABL1TSHRRIN1 | |
| SCHEMBL11959259 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPSR1ABL1TSHRRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200098-B2 | Radiation-sensitive composition and compound | JSR CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-9200098-B2 | Radiation-sensitive composition and compound | JSR CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20120164582-A1 | RADIATION-SENSITIVE COMPOSITION AND COMPOUND | JSR CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164582-A1 | RADIATION-SENSITIVE COMPOSITION AND COMPOUND | RAD51, RER1, ATP6AP1 | ALDH1A1 1300/4885NPSR1 3120/4885ABL1 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.