Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658362 | 0.85 | USP2 (0.49) | TNFKLF5NOD1USP2NPC1 | |
| SCHEMBL11321880 | 0.85 | AAK1 (0.46) | TNFKLF5NOD1USP2SMN1; SMN2 | |
| SCHEMBL10842026 | 0.84 | CYP2C19 (0.50) | TNFKLF5NOD1USP2NPC1 | |
| SCHEMBL10842020 | 0.84 | CYP2C19 (0.50) | TNFKLF5NOD1USP2NPC1 | |
| SCHEMBL11324498 | 0.80 | CES2 (0.46) | TNFKLF5NOD1USP2CDK5 | |
| SCHEMBL7045591 | 0.80 | ELANE (0.41) | TNFKLF5NOD1USP2NPC1 | |
| SCHEMBL11324501 | 0.80 | CES2 (0.46) | TNFKLF5NOD1USP2CDK5 | |
| SCHEMBL409974 | 0.78 | PLA2G7 (0.50) | TNFKLF5NOD1USP2RAB9A | |
| SCHEMBL209659 | 0.78 | PLA2G7 (0.50) | TNFKLF5NOD1USP2RAB9A | |
| SCHEMBL209658 | 0.78 | PLA2G7 (0.50) | TNFKLF5NOD1USP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020108-A2 | MULTIMERIC INHIBITORS OF VIRAL FUSION AND USES THEREOF | CORMUS SRL (IT) | 2012-02-16 | — | — | WO | disclosed |