SCHEMBL10174232

SCHEMBL10174232

CCC(C)(C)C(=O)Nc1ccc(CC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 7/20 0.56
MITF O75030 1/20 0.54
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
HSD17B10 Q99714 1/20 0.50
FFAR1 O14842 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
RIPK1 Q13546 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12226380 0.86 L3MBTL1 (0.61) MEN1KMT2APOLBTDP1RIPK1
SCHEMBL10075598 0.85 MEN1 (0.53) MEN1KMT2APOLBTDP1RIPK1
SCHEMBL10174230 0.84 NR1H4 (0.58) NR1H4MEN1KMT2AFFAR1TDP1
SCHEMBL10159848 0.83 MEN1 (0.51) MEN1KMT2APOLBTDP1RIPK1
SCHEMBL12205961 0.82 MEN1 (0.50) MEN1KMT2APOLBTDP1RIPK1
SCHEMBL750651 0.81 RIPK1 (0.59) MEN1KMT2APOLBSMN1; SMN2HSD17B10
SCHEMBL12226381 0.81 L3MBTL1 (0.73) MEN1KMT2APOLBSMN1; SMN2TDP1
SCHEMBL6807344 0.81 L3MBTL1 (0.61) MEN1KMT2APOLBTDP1RIPK1
SCHEMBL12205982 0.80 RIPK1 (0.59) MEN1KMT2AFFAR1RIPK1
SCHEMBL802226 0.80 EPHX2 (0.54) NR1H4MITFMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124317-B2 Planographic printing plate precursor and method of producing a copolymer used therein FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087787-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING A COPOLYMER USED THEREIN FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed