Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | MMP12 | P39900 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282173 | 0.86 | LMNA (0.49) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL28607697 | 0.75 | LMNA (0.48) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL5065716 | 0.73 | LMNA (0.47) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL28921632 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRMMP1MMP12MMP9 | |
| SCHEMBL17797870 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRSMN1; SMN2MAPTLMNA | |
| SCHEMBL10503868 | 0.73 | HSD17B10 (0.46) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL10504114 | 0.73 | CYP4F2 (0.47) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL1160497 | 0.73 | LMNA (0.55) | ALDH1A1TSHRSMN1; SMN2MMP2HSD17B10 | |
| SCHEMBL27623880 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL21060952 | 0.72 | HIF1A (0.49) | ALDH1A1MMP1MMP12MMP9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148371-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-7754728-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, P2RY10, HRH4 | ALDH1A1 867/4885TSHR 3638/4885MMP1 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.