Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | CASP7 | P55210 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP4 | P49662 | 2/20 | 0.51 |
| ▸ | CASP9 | P55211 | 2/20 | 0.50 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134450 | 0.89 | ECE1 (0.54) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL919245 | 0.89 | MAPK1 (0.53) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL4582904 | 0.89 | MAPK1 (0.53) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL4582911 | 0.89 | MAPK1 (0.53) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL9829175 | 0.88 | ECE1 (0.53) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL9829163 | 0.88 | ECE1 (0.53) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL9556695 | 0.86 | MAPK1 (0.51) | CTSLCTSSECE1CYP3A4MME | |
| SCHEMBL28176769 | 0.85 | ATM (0.60) | CTSLCTSSCYP3A4ATMTSHR | |
| SCHEMBL25495058 | 0.83 | ATM (0.57) | CTSLCTSSCYP3A4ATMTSHR | |
| SCHEMBL28355584 | 0.83 | CYP3A4 (0.57) | CTSLCTSSCYP3A4ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107902-A1 | Processes For Forming Amide Bonds And Compositions Related Thereto | EMORY UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107902-A1 | Processes For Forming Amide Bonds And Compositions Related Thereto | TMT1A, LPO, GSTO1 | CTSL 2981/4885CTSS 2126/4885ECE1 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.