Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582911 | 1.00 | MAPK1 (0.53) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL919245 | 1.00 | MAPK1 (0.53) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL9556695 | 0.97 | MAPK1 (0.51) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL30134450 | 0.95 | ECE1 (0.54) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL9829175 | 0.92 | ECE1 (0.53) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL9829163 | 0.92 | ECE1 (0.53) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL23086205 | 0.89 | MEN1 (0.60) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL23086208 | 0.89 | MEN1 (0.60) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL23086206 | 0.89 | MEN1 (0.60) | MAPK1ECE1CYP3A4MMEALDH1A1 | |
| SCHEMBL10175007 | 0.89 | CTSL (0.55) | MAPK1ECE1CYP3A4MMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083220-A1 | LIGAND-OLIGONUCLEOTIDE CONJUGATE AND LINKER FOR CONJUGATE | 上海京新生物医药有限公司 | 2024-04-25 | — | — | WO | disclosed |
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-0755374-B1 | PROCESS FOR PEPTIDE SEGMENT CONDENSATION | MERCK & CO INC (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-0755374-A4 | PROCESS FOR PEPTIDE SEGMENT CONDENSATION | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5773575-A | REACTING A CARBOXYLIC ACID AND AMINE WITH COUPLING AGENT | MERCK & CO., INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0755374-A1 | PROCESS FOR PEPTIDE SEGMENT CONDENSATION | Merck & Co., Inc. (a New Jersey corp.) (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5502165-A | AMIDATION OF CARBOXY COMPOOUND WITH AMINE IN WATER AND SOLVENT | MERCK & CO., INC. (US) | 1996-03-26 | — | — | US | disclosed |
| WO-1995027727-A2 | PROCESS FOR PEPTIDE SEGMENT CONDENSATION | MERCK & CO., INC. (US) | 1995-10-19 | — | — | WO | disclosed |