Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829163 | 1.00 | ECE1 (0.53) | ECE1MMERENCYP3A4MAPK1 | |
| SCHEMBL30134450 | 0.92 | ECE1 (0.54) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL4582904 | 0.92 | MAPK1 (0.53) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL4582911 | 0.92 | MAPK1 (0.53) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL919245 | 0.92 | MAPK1 (0.53) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL9556695 | 0.89 | MAPK1 (0.51) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL9574224 | 0.88 | ECE1 (0.62) | ECE1MMECTSLCTSSMEN1 | |
| SCHEMBL9325847 | 0.88 | ECE1 (0.62) | ECE1MMECTSLCTSSMEN1 | |
| SCHEMBL10175007 | 0.88 | CTSL (0.55) | ECE1MMECYP3A4MAPK1CTSL | |
| SCHEMBL9324497 | 0.86 | MAPK1 (0.55) | ECE1MMECYP3A4MAPK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |