⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833284 | 1.00 | — | — | |
| SCHEMBL599696 | 1.00 | — | — | |
| SCHEMBL27360126 | 0.97 | ALDH1A1 (0.52) | — | |
| Iodomethane SCHEMBL8981617 | 0.95 | ALDH1A1 (0.50) | — | |
| SCHEMBL30213431 | 0.88 | ALDH1A1 (0.44) | — | |
| Levulinic Acid SCHEMBL30924217 | 0.86 | LMNA (0.61) | — | |
| SCHEMBL2343475 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL27571000 | 0.79 | KDM4E (0.44) | — | |
| SCHEMBL791253 | 0.79 | — | — | |
| SCHEMBL2599566 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207355-A1 | PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG | L-Base Co., Ltd. (KR) | 2024-06-27 | — | — | US | disclosed |
| US-20230234917-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES INC (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230159587-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | L-Base Co., Ltd. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20170252356-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING HIV WITH DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC | 2017-09-07 | — | — | US | disclosed |
| US-20160176906-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2016-06-23 | — | — | US | disclosed |
| US-9340513-B2 | Propenoate derivatives of betulin | GLAXOSMITHKLINE LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160120878-A1 | DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC | 2016-05-05 | — | — | US | disclosed |
| US-9248140-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2016-02-02 | — | — | US | disclosed |
| US-20150328239-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2015-11-19 | — | — | US | disclosed |
| US-9102685-B2 | Derivatives of betulin | GLAXOSMITHKLINE LLC (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150218142-A1 | Derivatives of Betulin | GLAXOSMITHKLINE LLC (US) | 2015-08-06 | — | — | US | disclosed |
| US-9018381-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2015-04-28 | — | — | US | disclosed |
| US-20140357643-A1 | Derivatives of Betulin | GLAXOSMITHKLINE LLC | 2014-12-04 | — | — | US | disclosed |
| US-20140350032-A1 | PROPENOATE DERIVATIVES OF BETULIN | GLAXOSMITHKLINE LLC | 2014-11-27 | — | — | US | disclosed |
| EP-2799912-A1 | OPTICAL MEMBER SET AND SOLID-STATE IMAGE PICKUP ELEMENT USING SAME | FUJI-FILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20130310344-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (UK) | 2013-11-21 | — | — | US | disclosed |
| US-20130184263-A1 | Derivatives of Betulin | GLAXOSMITHKLINE LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20120035134-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | US | disclosed |