SCHEMBL10175353

SCHEMBL10175353

CC1(C(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)F)CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13744387 0.84 USP2 (0.31) USP2MAPTTSHR
SCHEMBL472018 0.82 P2RX7 (0.34) CYP2C19P2RX7
SCHEMBL5347783 0.79 P2RX7 (0.35) CYP2C19P2RX7
SCHEMBL17147582 0.76 P2RX7 (0.34) CYP2C19P2RX7
SCHEMBL2682160 0.74
SCHEMBL200228 0.74 CYP2C19 (0.40) TSHRCYP1A2CYP2C19P2RX7
SCHEMBL1451060 0.73 CETP (0.37) TSHRCYP2C19P2RX7
SCHEMBL203304 0.73 P2RX7 (0.36) CYP2C19P2RX7
SCHEMBL18938394 0.72 P2RX7 (0.41) MAPTTSHRCYP1A2CYP2C19P2RX7
SCHEMBL200115 0.72 P2RX7 (0.41) MAPTTSHRCYP1A2CYP2C19P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088537-B2 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-03 US disclosed
US-20090197200-A1 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-06 US disclosed