Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782074 | 0.97 | TSHR (0.43) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28380244 | 0.97 | TSHR (0.43) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4748717 | 0.85 | GABRA1 (0.42) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7323816 | 0.83 | TSHR (0.39) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30169568 | 0.83 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30354037 | 0.83 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL197690 | 0.83 | ACHE (0.64) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1752721 | 0.83 | MEN1 (0.39) | TSHRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14878582 | 0.80 | MYC (0.48) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29763044 | 0.80 | MYC (0.48) | TSHRACHENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-09-28 | — | — | US | disclosed |
| CN-110177798-B | Catalyst and process for preparing same | 博里利斯股份公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114921391-A | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-106905215-B | Process for preparing 1-H-pyrrolidine-2, 4-dione derivatives | 拜耳知识产权有限责任公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110167916-A | The manufacturing method of aromatic diamine compound precursor | 日产化学株式会社 | 2019-08-23 | — | — | CN | disclosed |
| CN-110023315-A | Novel compound or pharmacologically acceptable salt thereof | 国立研究开发法人理化学研究所 | 2019-07-16 | — | — | CN | disclosed |
| CN-109641899-A | Compounds and compositions as endosomal Toll-like receptor inhibitors | 诺华股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109563242-A | The manufacturing method of high-molecular compound | 住友化学株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-103459370-A | Process for preparing 1-H-pyrrolidine-2, 4-dione derivatives | BAYER IP GMBH | 2013-12-18 | — | — | CN | disclosed |
| US-20130217876-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE INC. (US) | 2013-08-22 | — | — | US | disclosed |
| CN-102858849-A | Photoaligning material | ROLIC AG | 2013-01-02 | — | — | CN | disclosed |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-26 | — | — | US | disclosed |
| CN-1762957-B | 2,3-dihydro-1-indene compound and preparation method thereof | BASELL POLYOLEFINE GMBH | 2010-05-12 | — | — | CN | disclosed |
| CN-100451024-C | Metallocene compound, indene compound and application thereof | BASELL POLYOLEFINE GMBH (DE) | 2009-01-14 | — | — | CN | disclosed |
| CN-1762957-A | 2,3-dihydro-1-indene compound and preparation method thereof | BASELL POLYOLEFINE GMBH (DE) | 2006-04-26 | — | — | CN | disclosed |
| CN-1763060-A | Metallocene compound, indene compound and application thereof | BASELL POLYOLEFINE GMBH (DE) | 2006-04-26 | — | — | CN | disclosed |
| CN-1231431-C | Process for preparing substituted 2, 3-dihydro-1-indanones | TARGOR GMBH (DE) | 2005-12-14 | — | — | CN | disclosed |
| CN-1254328-A | Process for preparing substituted 2, 3-dihydro-1-indanones | TARGOR GMBH (DE) | 2000-05-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217876-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | PHOSPHO1, PLCG2, PPIP5K2 | TSHR 3889/4885ACHE 208/4885NPC1 3879/4885 |
| US-20230309388-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE | OCIAD1, OCIAD2, SLCO4C1 | TSHR 4318/4885ACHE 1667/4885NPC1 967/4885 |
| US-20120022252-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | PHOSPHO1, PPIP5K2, ITPA | TSHR 2675/4885ACHE 106/4885NPC1 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.