Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10177352 | 0.85 | TSHR (0.45) | TSHRALDH1A1HPGDCA2NPC1 | |
| SCHEMBL782074 | 0.83 | TSHR (0.43) | TSHRALDH1A1HPGDCA2NPC1 | |
| Hydrochloric Acid SCHEMBL28380244 | 0.83 | TSHR (0.43) | TSHRALDH1A1TDP1HPGDCA2 | |
| SCHEMBL20034068 | 0.81 | GABRA1 (0.50) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL9960735 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL28153792 | 0.76 | CA2 (0.38) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL18307741 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL2220167 | 0.74 | ALDH1A1 (0.50) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL2911757 | 0.73 | GABRA1 (0.68) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL15251935 | 0.72 | ALDH1A1 (0.48) | GABRA1GABRB2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |