SCHEMBL10178611

SCHEMBL10178611

CCC(C)c1ccc(COc2ccc3c(ccc4ccccc43)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
NPC1 O15118 3/20 0.43
RAB9A P51151 2/20 0.43
BCHE P06276 2/20 0.42
MAPT P10636 1/20 0.42
HSP90AA1 P07900 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP3A4 P08684 2/20 0.40
CYP26A1 O43174 1/20 0.40
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14866949 0.91 ALOX5 (0.61) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL10178636 0.89 ALOX5 (0.55) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL14118572 0.82 RAB9A (0.55) ALOX5NPC1RAB9ABCHEHSP90AA1
SCHEMBL14461691 0.82 ALOX5 (0.61) ALOX5NPC1RAB9ABCHECYP3A4
SCHEMBL14866835 0.82 SMN1; SMN2 (0.39) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL10178565 0.81 ALOX5 (0.46) ALOX5BCHECYP3A4F2
SCHEMBL14118385 0.81 ALOX5 (0.41) ALOX5NPC1RAB9A
SCHEMBL14118326 0.80 NPC1 (0.49) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL2806115 0.79 ALOX5 (0.69) ALOX5NPC1RAB9AMAPTCYP3A4
SCHEMBL14118645 0.79 ALDH1A1 (0.46) NPC1RAB9ABCHEHSP90AA1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed