SCHEMBL10178636

SCHEMBL10178636

CCC(C)c1ccc(COc2ccc3cc4ccccc4cc3c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
BCHE P06276 2/20 0.46
MAPT P10636 1/20 0.46
HSP90AA1 P07900 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP3A4 P08684 2/20 0.43
F2 P00734 1/20 0.43
CYP26A1 O43174 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14866949 0.96 ALOX5 (0.61) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL10178611 0.89 ALOX5 (0.50) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL14461691 0.87 ALOX5 (0.61) ALOX5NPC1RAB9ABCHECYP3A4
SCHEMBL14118572 0.87 RAB9A (0.55) ALOX5NPC1RAB9ABCHEHSP90AA1
SCHEMBL10178738 0.86 ALOX5 (0.53) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL2806115 0.83 ALOX5 (0.69) ALOX5NPC1RAB9AMAPTCYP3A4
SCHEMBL6722051 0.82 BCHE (0.56) ALOX5NPC1RAB9ABCHEHSP90AA1
SCHEMBL10053088 0.82 BCHE (0.60) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL28572476 0.82 BCHE (0.60) ALOX5NPC1RAB9ABCHEMAPT
SCHEMBL825353 0.81 ALDH1A1 (0.49) ALOX5NPC1RAB9AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed