SCHEMBL10178738

SCHEMBL10178738

CCC(C)c1cccc(COc2ccc3cc4ccccc4cc3c2)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.53
MRGPRX4 Q96LA9 1/20 0.48
BCHE P06276 2/20 0.45
F2 P00734 1/20 0.43
CYP3A4 P08684 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178565 0.88 ALOX5 (0.46) ALOX5MRGPRX4BCHEF2CYP3A4
SCHEMBL10178636 0.86 ALOX5 (0.55) ALOX5BCHEF2CYP3A4NPC1
SCHEMBL14461691 0.85 ALOX5 (0.61) ALOX5BCHECYP3A4NPC1RAB9A
SCHEMBL10178653 0.84 BCHE (0.53) ALOX5MRGPRX4BCHESMN1; SMN2MAOB
SCHEMBL10178709 0.82 FFAR1 (0.48) MRGPRX4BCHE
SCHEMBL10178751 0.82 FFAR1 (0.53) ALOX5MRGPRX4BCHEMAOB
SCHEMBL14866949 0.82 ALOX5 (0.61) ALOX5MRGPRX4BCHEF2CYP3A4
SCHEMBL28346872 0.81 BCHE (0.60) ALOX5BCHESMN1; SMN2MAOB
SCHEMBL11922929 0.81 BCHE (0.60) ALOX5BCHESMN1; SMN2MAOB
SCHEMBL10179165 0.81 HDAC4 (0.38) ALOX5MRGPRX4BCHEHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed