Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178711 | 0.75 | PLA2G4B (0.37) | ALDH1A1HSD17B10KDM4ETDP1LMNA | |
| SCHEMBL10178960 | 0.75 | PLA2G4B (0.45) | ALDH1A1MAPTL3MBTL1POLBHSD17B10 | |
| SCHEMBL10178796 | 0.74 | KMT2A (0.41) | ALDH1A1MAPTHPGDHSD17B10LMNA | |
| SCHEMBL10180281 | 0.74 | PLA2G4B (0.39) | HSD17B10NPSR1TSHR | |
| SCHEMBL155116 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL1532561 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL4624403 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL10998807 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL11002356 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL1532451 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
| US-7723409-B2 | Coupling agents between filler and elastomer | CIBA SPECIALTY CHEM. CORP. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080287578-A1 | Coupling Agents Between Filler and Elastomer | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | ALDH1A1 1605/4885MAPT 2735/4885HPGD 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.