SCHEMBL10178796

SCHEMBL10178796

CCO[Si](CCCSCCC(=O)Oc1ccc(OC(=O)CCSCCC[Si](OCC)(OCC)OCC)cc1)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PLA2G4B P0C869 1/20 0.40
BCL9 O00512 1/20 0.38
CTNNB1 P35222 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ESR1 P03372 2/20 0.36
HIF1A Q16665 2/20 0.36
RECQL P46063 1/20 0.36
MEN1 O00255 3/20 0.35
SLC22A2 O15244 1/20 0.35
TMPRSS2 O15393 1/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PLG P00747 1/20 0.35
F12 P00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178811 0.81 TSHR (0.39) KMT2AALDH1A1LMNAHTTHSD17B10
SCHEMBL10178960 0.79 PLA2G4B (0.45) ALDH1A1MAPTLMNAHSD17B10PLA2G4B
SCHEMBL10178711 0.78 PLA2G4B (0.37) ALDH1A1LMNAHTTHSD17B10PLA2G4B
SCHEMBL9881102 0.78 PLA2G4B (0.42) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL15298642 0.77 ALDH1A1 (0.34) KMT2AALDH1A1LMNAHSD17B10PLA2G4B
SCHEMBL6391711 0.77 HSD17B10 (0.48) KMT2AALDH1A1MAPTLMNAHSD17B10
SCHEMBL10180281 0.77 PLA2G4B (0.39) HSD17B10PLA2G4B
SCHEMBL6391760 0.77 HDAC3 (0.32) KMT2AALDH1A1LMNAMEN1HPGD
SCHEMBL10180397 0.76 NAAA (0.41) SMN1; SMN2
SCHEMBL10178984 0.75 TSHR (0.32) ALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119710-B2 Filled rubber compounds with improved processability BASF SE (DE) 2012-02-21 US disclosed
US-20100317778-A1 Filled Rubber Compounds with Improved Processability CIBA CORPORATION 2010-12-16 US disclosed
US-7723409-B2 Coupling agents between filler and elastomer CIBA SPECIALTY CHEM. CORP. (US) 2010-05-25 US disclosed
US-20080287578-A1 Coupling Agents Between Filler and Elastomer CIBA SPECIALTY CHEMICALS CORP. 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317778-A1 Filled Rubber Compounds with Improved Processability RER1, RIF1, REV1 KMT2A 2949/4885ALDH1A1 1605/4885MAPT 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.