SCHEMBL10179600

SCHEMBL10179600

CCc1ccccc1S(=O)(=O)C(F)C(F)F

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSB P07858 1/20 0.45
HSD11B1 P28845 2/20 0.41
LOXL2 Q9Y4K0 2/20 0.37
PSIP1 O75475 1/20 0.36
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GABRA1 P14867 3/20 0.33
GABRB2 P47870 3/20 0.33
KAT6A Q92794 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10181391 0.86 GABRA1 (0.40) CTSBGABRA1GABRB2
SCHEMBL21148177 0.79 CTSB (0.49) CTSBHSD11B1LOXL2PSIP1GABRA1
SCHEMBL10180086 0.76 TSHR (0.44) HSD11B1PSIP1SMN1; SMN2
SCHEMBL10180625 0.76 NPC1 (0.37) HSD11B1PSIP1NPC1LMNAMAPK1
SCHEMBL10179992 0.74 HSD11B1 (0.42) HSD11B1ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL10180863 0.74 HSD11B1 (0.47) HSD11B1ALDH1A1NPC1LMNAMAPT
SCHEMBL780568 0.73 CTSB (0.55) CTSBHSD11B1LOXL2PSIP1GABRA1
SCHEMBL22780507 0.71 CTSB (0.48) CTSBHSD11B1LOXL2PSIP1MAPT
SCHEMBL2024322 0.71 CTSB (0.53) CTSBHSD11B1LOXL2PSIP1ALDH1A1
SCHEMBL10179924 0.71 CTSB (0.53) CTSBHSD11B1LOXL2PSIP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed