Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256900 | 0.88 | PLCG1 (0.54) | CTSBPSIP1HSD11B1LOXL2GABRA1 | |
| SCHEMBL28680071 | 0.85 | PSIP1 (0.59) | CTSBPSIP1HSD11B1PLCG1MAPT | |
| SCHEMBL10181520 | 0.85 | PSIP1 (0.45) | CTSBPSIP1HSD11B1TAAR1PLCG1 | |
| SCHEMBL4598904 | 0.85 | PSIP1 (0.45) | CTSBPSIP1LOXL2PLCG1DDR1 | |
| SCHEMBL9987989 | 0.85 | PSIP1 (0.45) | CTSBPSIP1HSD11B1LOXL2PLCG1 | |
| SCHEMBL19617799 | 0.85 | PSIP1 (0.45) | CTSBPSIP1HSD11B1GABRA1GABRB2 | |
| SCHEMBL780568 | 0.83 | CTSB (0.55) | CTSBPSIP1HSD11B1LOXL2GABRA1 | |
| Hydrochloric Acid SCHEMBL7370334 | 0.83 | LOXL2 (0.44) | CTSBPSIP1HSD11B1LOXL2PLCG1 | |
| SCHEMBL4598969 | 0.81 | TAAR1 (0.48) | CTSBPSIP1LOXL2TAAR1 | |
| SCHEMBL12004765 | 0.81 | PSIP1 (0.42) | CTSBPSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |
| US-20130244122-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME | ONUKI MASAMICHI (JP) | 2013-09-19 | — | — | US | disclosed |
| US-20120219866-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2012-08-30 | — | — | US | disclosed |
| EP-2475041-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME | Mitsubishi Chemical Corporation (JP) | 2012-07-11 | — | — | EP | disclosed |