Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.39 |
| ▸ | PRKCH | P24723 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | LATS1 | O95835 | 6/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK14 | O94921 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.32 |
| ▸ | CDK17 | Q00537 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462894 | 0.84 | CCNT1 (0.45) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL1462988 | 0.77 | CCNT1 (0.48) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL1462844 | 0.75 | AOC2 (0.31) | — | |
| SCHEMBL1463729 | 0.73 | CDK9 (0.75) | CCNT1CDK9 | |
| SCHEMBL1949578 | 0.73 | CDK9 (0.59) | CCNT1CDK9CCNK | |
| SCHEMBL1225997 | 0.72 | ADORA2B (0.35) | CCNT1DYRK1B | |
| SCHEMBL1192405 | 0.72 | CCNT1 (0.48) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL1463745 | 0.72 | CDK9 (0.54) | CCNT1CDK9CCNKCDK1CCNA2 | |
| SCHEMBL1463738 | 0.71 | CCNT1 (0.47) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL1945842 | 0.71 | CCNT1 (0.47) | CCNT1CDK9CCNKCDK14CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | claimed |