Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655554 | 0.79 | TSHR (0.46) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL28734969 | 0.78 | TSHR (0.68) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL9798184 | 0.76 | CA1 (0.41) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL4574471 | 0.75 | TSHR (0.41) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL19417918 | 0.75 | CA1 (0.41) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL11698176 | 0.75 | CA1 (0.37) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL7936908 | 0.75 | CA1 (0.37) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL97582 | 0.74 | CA1 (0.52) | TSHRTDP1CA1CA2IDO1 | |
| SCHEMBL17092743 | 0.72 | CA1 (0.38) | TSHRMAPK1TDP1ATML3MBTL1 | |
| SCHEMBL51783 | 0.72 | IDO1 (0.52) | TSHRMAPK1TDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232255-A1 | PRETREATMENT CARTRIDGE FOR SEPARATING SUBSTANCE AND METHOD OF PRETREATMENT USING THE SAME | TERUO OKANO (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2474827-A1 | PRETREATMENT CARTRIDGE FOR SEPARATING SUBSTANCE AND METHOD OF PRETREATMENT USING SAME | CellSeed Inc. (JP) | 2012-07-11 | — | — | EP | disclosed |