SCHEMBL5655554

SCHEMBL5655554

ClCc1ccc(C(Cl)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MAPK1 P28482 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798184 0.80 CA1 (0.41) TSHRCA1CA2MAPK1ATM
SCHEMBL19417918 0.79 CA1 (0.41) TSHRCA1CA2MAPK1ATM
SCHEMBL7936908 0.79 CA1 (0.37) TSHRCA1CA2MAPK1ATM
SCHEMBL11698176 0.79 CA1 (0.37) TSHRCA1CA2MAPK1ATM
SCHEMBL10179845 0.79 TSHR (0.41) TSHRCA1CA2MAPK1ATM
SCHEMBL4574471 0.79 TSHR (0.41) TSHRCA1CA2MAPK1ATM
SCHEMBL97582 0.78 CA1 (0.52) TSHRCA1CA2TDP1FAAH
SCHEMBL5075045 0.78 TSHR (0.67) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL5267546 0.76 CA1 (0.43) TSHRCA1CA2MAPK1ATM
SCHEMBL9397388 0.76 TSHR (0.43) TSHRMAPK1ATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US claimed
US-5080767-A Light an dpolyalkylene-amine are present MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-14 US claimed
EP-0391696-A2 Process for preparing aromatic compounds having chlorinated side chains and method for stabilizing monochloro-side chain aromatic compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-10 EP claimed
US-4328374-A Process for the production of aromatic dialdehydes MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1982-05-04 US claimed
JP-8048755-A None JP disclosed
JP-2275834-A None JP disclosed
JP-2275833-A None JP disclosed
JP-4066547-A None JP disclosed
JP-56010129-A None JP disclosed
JP-54125628-A None JP disclosed
JP-4059741-A None JP disclosed
CN-111704534-A Process for continuously and industrially producing terephthalaldehyde by using microchannel reactor 杭州迈科瑞科技有限公司 2020-09-25 CN disclosed
US-4465865-A Method of preparing terephthalic aldehyde and isophthalic aldehyde DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed
US-4399311-A Process for producing aromatic aldehydes MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-08-16 US disclosed
US-4328374-A Process for the production of aromatic dialdehydes MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1982-05-04 US disclosed
US-4328374-A Process for the production of aromatic dialdehydes MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1982-05-04 US disclosed
JP-S5610129-A PREPARATION OF AROMATIC DIALDEHYDE MITSUBISHI GAS CHEM CO INC 1981-02-02 JP disclosed
JP-S54125628-A PREPARATION OF P-(CHLOROMETHYL) BENZALDEHYDE BANYU PHARMACEUT CO LTD 1979-09-29 JP disclosed
US-4166075-A IRON HALIDE OR ANTIMONY HALIDE AND A COCATALYST SELECTED FROM ALCOHOLS, ACIDS, KETONES, OR ALDEHYDES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-08-28 US disclosed
US-4010214-A FROM P-XYLENE AND CHLORINE, IRON HALIDE ANDOR ANTIMONY HALIDE AND ORGANIC SULFUR COMPOUND CATALYST HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-03-01 US disclosed