Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179924 | 0.88 | CTSB (0.53) | PLCG1CTSBPSIP1HSD11B1LOXL2 | |
| SCHEMBL780568 | 0.81 | CTSB (0.55) | CTSBPSIP1HSD11B1LOXL2KMT2A | |
| SCHEMBL10180368 | 0.79 | TSHR (0.56) | CTSBLOXL2KMT2ATAAR1POLB | |
| SCHEMBL330706 | 0.79 | CTSB (0.53) | PLCG1CTSBPSIP1HSD11B1LOXL2 | |
| SCHEMBL2024322 | 0.79 | CTSB (0.53) | CTSBPSIP1HSD11B1LOXL2KMT2A | |
| SCHEMBL28539386 | 0.78 | MMP2 (0.49) | CTSBPSIP1HSD11B1KMT2ATAAR1 | |
| SCHEMBL10179598 | 0.78 | HSD11B1 (0.48) | CTSBPSIP1HSD11B1LOXL2KMT2A | |
| SCHEMBL5412466 | 0.78 | ALDH1A1 (0.47) | PLCG1CTSBPSIP1HSD11B1LOXL2 | |
| SCHEMBL29394818 | 0.77 | CTSB (0.52) | CTSBPSIP1HSD11B1LOXL2KMT2A | |
| SCHEMBL301742 | 0.77 | CA2 (0.52) | CTSBHSD11B1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1992612-A1 | 1-FLUORO-1,1-BIS(PHENYLSULFONYL)METHANE AND METHOD FOR PRODUCING SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | PLCG1 1435/4885CTSB 1720/4885PSIP1 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.