Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179692 | 0.95 | GPR119 (0.41) | GPR119PRMT5 | |
| SCHEMBL10179554 | 0.87 | GPR119 (0.45) | GPR119 | |
| SCHEMBL10179268 | 0.85 | PRMT5 (0.41) | GPR119PRMT5 | |
| SCHEMBL10179091 | 0.81 | GPR119 (0.45) | GPR119DRD3HTR6HRH3 | |
| SCHEMBL10179883 | 0.78 | DRD2 (0.36) | GPR119PRMT5HRH3 | |
| SCHEMBL10181085 | 0.78 | CCR2 (0.38) | GPR119PRMT5 | |
| SCHEMBL10180791 | 0.78 | IRAK4 (0.37) | GPR119PRMT5 | |
| SCHEMBL10179713 | 0.78 | GPR119 (0.39) | GPR119PRMT5 | |
| SCHEMBL10179608 | 0.77 | THRA (0.35) | GPR119PRMT5 | |
| SCHEMBL1577441 | 0.77 | GPR119 (0.44) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474540-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |