Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.30 |
| ▸ | ABAT | P80404 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880077 | 0.87 | ALDH1A1 (0.35) | ALDH1A3ALDH1A1TSHRRAB9AAOX1 | |
| SCHEMBL321346 | 0.74 | ALDH1A3 (0.47) | ALDH1A3ALDH1A1ALDH3A1TSHRNPC1 | |
| SCHEMBL3280683 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL29417742 | 0.68 | KIF11 (0.51) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A | |
| SCHEMBL7147339 | 0.68 | KIF11 (0.51) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A | |
| SCHEMBL14593109 | 0.65 | ALDH1A3 (0.41) | ALDH1A3ALDH1A1ALDH3A1TSHRNPC1 | |
| SCHEMBL3631166 | 0.64 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1ALDH3A1TSHRNPC1 | |
| SCHEMBL8894104 | 0.63 | CA1 (0.32) | ALDH1A1 | |
| SCHEMBL154851 | 0.63 | ALDH1A3 (0.53) | ALDH1A3ALDH1A1ALDH3A1TSHRNPC1 | |
| SCHEMBL870202 | 0.62 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114873-B1 | N-[3-BROMO-4-(3- [18F]FLUOROPROPOXY)-BENZYL]-GUANIDINE FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING INC (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2474523-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474526-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474524-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |