Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NAT1 | P18440 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880077 | 0.77 | ALDH1A1 (0.35) | ALDH1A1RAB9ATDP1TSHRCYP2A6 | |
| SCHEMBL10180277 | 0.74 | ALDH1A3 (0.37) | ALDH1A1NPC1RAB9ATDP1TSHR | |
| SCHEMBL3747673 | 0.73 | MGLL (0.47) | ALDH1A1 | |
| SCHEMBL6848985 | 0.73 | ALDH1A1 (0.48) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL309484 | 0.73 | ALDH1A1 (0.48) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL29846591 | 0.73 | ALDH1A1 (0.48) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL669370 | 0.70 | ALDH1A1 (0.42) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL15352523 | 0.70 | ALDH1A1 (0.45) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL6854509 | 0.70 | ESR1 (0.52) | ALDH1A1UNGSRCMAOAMAOB | |
| SCHEMBL5778960 | 0.70 | ALDH1A1 (0.45) | ALDH1A1UNGSRCMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |