SCHEMBL10180374

SCHEMBL10180374

CCc1cccc(S(=O)(=O)C(F)(F)CF)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.40
KAT6A Q92794 2/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
TNF P01375 1/20 0.36
NOD1 Q9Y239 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180743 0.88 KAT6A (0.41) KAT6ANPC1RAB9ALMNATNF
SCHEMBL10181301 0.85 TRPV1 (0.41) SMN1; SMN2HTR6METAP2
SCHEMBL10182305 0.85 LMNA (0.45) LOXL2KAT6ANPC1RAB9AMAPT
SCHEMBL10180466 0.83 HTR2A (0.39) NPC1RAB9AMAPTALDH1A1LMNA
SCHEMBL10181398 0.80 CA2 (0.50) MAPTALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL10179537 0.77 ACHE (0.47) ALDH1A1HDAC3HDAC4HDAC2HDAC11
SCHEMBL10181254 0.77 LMNA (0.41) NPC1RAB9AMAPTALDH1A1LMNA
SCHEMBL10180810 0.77 HDAC4 (0.44) KAT6AALDH1A1SMN1; SMN2HDAC4HDAC2
SCHEMBL10179562 0.76 KAT6A (0.38) KAT6AMAPTALDH1A1SMN1; SMN2HDAC4
SCHEMBL10180377 0.75 LOXL2 (0.41) LOXL2KAT6ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed