SCHEMBL10180397

SCHEMBL10180397

CCO[Si](CCCSCCC(=O)OC1CCC(OC(=O)CCSCCC[Si](OCC)(OCC)OCC)CC1)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.41
CYP19A1 P11511 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178851 0.95 NAAA (0.49) NAAACYP19A1SMN1; SMN2EPHX1
SCHEMBL10178811 0.82 TSHR (0.39)
SCHEMBL10178836 0.81 NAAA (0.48) NAAACYP19A1SMN1; SMN2EPHX1
SCHEMBL10178711 0.79 PLA2G4B (0.37) NAAA
SCHEMBL14353378 0.79 NAAA (0.44) NAAACYP19A1SMN1; SMN2
SCHEMBL15298642 0.79 ALDH1A1 (0.34)
SCHEMBL6391711 0.79 HSD17B10 (0.48)
SCHEMBL6391760 0.78 HDAC3 (0.32)
SCHEMBL10180281 0.78 PLA2G4B (0.39) NAAA
SCHEMBL10178964 0.78 ALDH1A1 (0.48) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119710-B2 Filled rubber compounds with improved processability BASF SE (DE) 2012-02-21 US disclosed
US-20100317778-A1 Filled Rubber Compounds with Improved Processability CIBA CORPORATION 2010-12-16 US disclosed
US-7723409-B2 Coupling agents between filler and elastomer CIBA SPECIALTY CHEM. CORP. (US) 2010-05-25 US disclosed
US-20080287578-A1 Coupling Agents Between Filler and Elastomer CIBA SPECIALTY CHEMICALS CORP. 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317778-A1 Filled Rubber Compounds with Improved Processability RER1, RIF1, REV1 NAAA 1369/4885CYP19A1 1085/4885SMN1; SMN2 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.