SCHEMBL10180427

SCHEMBL10180427

CCCc1cccc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.70
KAT6A Q92794 1/20 0.52
METAP2 P50579 1/20 0.47
SFRP1 Q8N474 1/20 0.47
CNR2 P34972 1/20 0.47
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 2/20 0.46
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
PSIP1 O75475 1/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27876496 0.94 HTR6 (0.61) HTR6KAT6AMETAP2SFRP1CNR2
SCHEMBL10180036 0.90 HTR6 (0.66) HTR6KAT6AMETAP2SFRP1CNR2
SCHEMBL12619358 0.85 HTR6 (0.53) HTR6KAT6ASFRP1CNR2ALDH1A1
SCHEMBL10180577 0.85 HTR6 (0.64) HTR6KAT6AMETAP2SFRP1ALDH1A1
SCHEMBL27859841 0.84 HTR6 (0.57) HTR6METAP2CNR2ALDH1A1SMN1; SMN2
SCHEMBL4618112 0.83 HTR6 (0.67) HTR6METAP2SFRP1CNR2ALDH1A1
SCHEMBL10180777 0.83 KAT6A (0.50) HTR6KAT6AMETAP2CNR2TSHR
SCHEMBL6444977 0.82 LPL (0.56) HTR6ALDH1A1SMN1; SMN2TSHR
SCHEMBL10180981 0.81 PSIP1 (0.52) HTR6KAT6AMETAP2CNR2ALDH1A1
SCHEMBL331256 0.81 KAT6A (0.48) HTR6KAT6AMETAP2CNR2PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed