SCHEMBL10180452

SCHEMBL10180452

CCCCCc1ccccc1OS(=O)(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
ALDH1A1 P00352 1/20 0.46
DHODH Q02127 1/20 0.46
PPARA Q07869 2/20 0.46
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PPARG P37231 1/20 0.44
LIPG Q9Y5X9 1/20 0.41
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MGLL Q99685 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180459 0.90 LMNA (0.48) THRATHRBALDH1A1DHODHALOX5
SCHEMBL8837788 0.89 DHODH (0.52) ALDH1A1DHODHTDP1METAP2METAP1
SCHEMBL10180574 0.85 HTT (0.50) THRBALDH1A1PPARATDP1PPARG
SCHEMBL11595077 0.84 THRA (0.48) THRATHRBPPARAALOX5PTGS2
SCHEMBL11791849 0.84 THRA (0.52) THRATHRBPPARAALOX5PTGS2
SCHEMBL1822181 0.84 DHODH (0.59) ALDH1A1DHODHTDP1METAP2METAP1
SCHEMBL5935094 0.83 ALDH1A1 (0.47) ALDH1A1DHODHTDP1METAP2METAP1
SCHEMBL10179746 0.83 THRA (0.49) THRATHRBPPARAALOX5PTGS2
SCHEMBL11654900 0.83 THRA (0.55) THRATHRBPPARAALOX5PTGS2
SCHEMBL10180566 0.83 THRA (0.51) THRATHRBPPARAALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed