Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499352 | 0.88 | DHODH (0.59) | DHODHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8837788 | 0.88 | DHODH (0.52) | DHODHALDH1A1MAPTL3MBTL1METAP2 | |
| SCHEMBL13724032 | 0.86 | DHODH (0.58) | DHODHALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10180452 | 0.84 | THRA (0.48) | DHODHALDH1A1MAPTL3MBTL1METAP2 | |
| SCHEMBL13723550 | 0.82 | DHODH (0.54) | DHODHALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL13723179 | 0.82 | DHODH (0.48) | DHODHALDH1A1METAP2METAP1TDP1 | |
| SCHEMBL31272384 | 0.82 | ALDH1A1 (0.68) | ALDH1A1MAPTL3MBTL1METAP2METAP1 | |
| SCHEMBL777281 | 0.80 | L3MBTL1 (0.50) | DHODHMAPTL3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL3580857 | 0.80 | DHODH (0.49) | DHODHALDH1A1MAPTL3MBTL1METAP2 | |
| SCHEMBL9510398 | 0.79 | DHODH (0.48) | DHODHALDH1A1MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-B1 | Intermediate for preparing a biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2014-08-13 | — | — | EP | disclosed |
| WO-2012142698-A1 | ALKYLUREA DERIVATIVES ACTIVE AGAINST CANCER CELLS | UNIVERSITE LAVAL (CA) | 2012-10-26 | — | — | WO | disclosed |
| EP-1481967-B1 | PROCESS FOR THE PREPARATION OF BIARYL COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2011-05-04 | — | — | EP | disclosed |
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |