Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180793 | 0.85 | MGLL (0.45) | MEN1KMT2AALDH1A1MGLLMAPT | |
| SCHEMBL5019122 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL13365288 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019032 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL964298 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL21880131 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL21880132 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL19688778 | 0.78 | MGLL (0.76) | MEN1KMT2AALDH1A1MGLLSMN1; SMN2 | |
| SCHEMBL8553761 | 0.78 | MEN1 (0.58) | MEN1KMT2AALDH1A1MGLLCYP1A2 | |
| SCHEMBL968952 | 0.77 | HDAC4 (0.60) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678168-B1 | P70S6 KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2012-07-11 | — | — | EP | disclosed |