Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664114 | 0.94 | DGAT1 (0.56) | DGAT1HSD17B10HPGDOPRM1OPRD1 | |
| SCHEMBL664113 | 0.94 | DGAT1 (0.56) | DGAT1HSD17B10HPGDOPRM1OPRD1 | |
| SCHEMBL10184323 | 0.94 | DGAT1 (0.56) | DGAT1HSD17B10HPGDOPRM1OPRD1 | |
| SCHEMBL10186147 | 0.93 | NPC1 (0.54) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL10184403 | 0.92 | DGAT1 (0.54) | DGAT1HSD17B10OPRM1OPRD1MEN1 | |
| SCHEMBL10185270 | 0.91 | MMP13 (0.57) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL10184332 | 0.91 | DGAT1 (0.51) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL10185162 | 0.89 | MTNR1B (0.51) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL10184898 | 0.88 | DGAT1 (0.52) | DGAT1HSD17B10LMNA | |
| SCHEMBL10185165 | 0.88 | DGAT1 (0.52) | CA12CA1CA2MMP2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | CA12 4203/4885CA1 4328/4885CA2 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.