Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18148192 | 0.90 | VCAM1 (0.57) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL2876988 | 0.88 | VCAM1 (0.55) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL29995132 | 0.88 | VCAM1 (0.55) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL2953971 | 0.88 | PDK1 (0.62) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL3085325 | 0.87 | VCAM1 (0.59) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL4262486 | 0.86 | KMT2A (0.61) | KMT2AHPGDALDH1A1PDK1LMNA | |
| SCHEMBL14412612 | 0.85 | VCAM1 (0.58) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL6953347 | 0.85 | PDK1 (0.46) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL20594403 | 0.84 | VCAM1 (0.57) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL5882061 | 0.84 | VCAM1 (0.57) | VCAM1KMT2AHPGDALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250249-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) | 2025-08-07 | — | — | US | disclosed |
| US-12312326-B2 | Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors | Tseng, Yufeng Jane (US) | 2025-05-27 | — | — | US | disclosed |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES | 2025-05-01 | — | — | US | disclosed |
| US-12129242-B2 | Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors | Tseng, Yufeng Jane (US) | 2024-10-29 | — | — | US | disclosed |
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240208969-A1 | SUBSTITUTED FUSED BICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF | IMPACT THERAPEUTICS (SHANGHAI), INC. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240159706-A1 | MALDI-MS METHOD, PHOTO-SENSITIVE MALDI MATRIX COMPOSITE AND PHOTO-CAGED MALDI MATRIX COMPOUND FOR USE IN SAID METHOD AND RESPECTIVE USES | SIRIUS FINE CHEMICALS SICHEM GMBH (DE) | 2024-05-16 | — | — | US | disclosed |
| CN-117653636-B | Anticancer medicine containing condensed bicyclo compound and pharmaceutical use of the compound | 上海瑛派药业有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20240132449-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. | 2024-04-25 | — | — | US | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| CN-1079648-A | Preparation contains the method for the pharmaceutical composition of imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1993-12-22 | — | — | CN | disclosed |
| US-5189033-A | Analgesics, antiiflammatory agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| EP-0480641-A1 | Tricyclic heterocycles | ZENECA LIMITED (GB) | 1992-04-15 | — | — | EP | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4551416-A | Process for preparing semiconductors using photosensitive bodies | AT&T BELL LABORATORIES (US) | 1985-11-05 | — | — | US | disclosed |
| US-4400461-A | O-NITROARYLMETHYL ESTERS OF CARBOXYLIC ACIDS, POLYMER | BELL TELEPHONE LABORATORIES, INCORPORATED (US) | 1983-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250249-A1 | NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS | DAO, DDO, DDC | VCAM1 3662/4885KMT2A 943/4885HPGD 720/4885 |
| US-20240208969-A1 | SUBSTITUTED FUSED BICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF | PARP1, PARP3, PARP11 | VCAM1 2073/4885KMT2A 1411/4885HPGD 396/4885 |
| US-12312326-B2 | Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors | DAO, DDO, DDC | VCAM1 3350/4885KMT2A 984/4885HPGD 631/4885 |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | SHH, GLI1, SMO | VCAM1 4796/4885KMT2A 1487/4885HPGD 2664/4885 |
| US-12129242-B2 | Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors | DAO, DDO, DDC | VCAM1 3350/4885KMT2A 984/4885HPGD 631/4885 |
| US-20240132449-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | PARP1, PARP11, PARP12 | VCAM1 2811/4885KMT2A 1465/4885HPGD 44/4885 |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | MLLT3, MLLT1, YEATS2 | VCAM1 1547/4885KMT2A 53/4885HPGD 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.