Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662784 | 0.88 | DGAT1 (0.46) | CCR3HRH3POLBKMT2AHPGD | |
| SCHEMBL10185451 | 0.88 | DGAT1 (0.46) | CCR3HRH3POLBKMT2AHPGD | |
| SCHEMBL662783 | 0.88 | DGAT1 (0.46) | CCR3HRH3POLBKMT2AHPGD | |
| SCHEMBL10186452 | 0.86 | FAAH (0.47) | FFAR4HRH3KMT2AEPHX2 | |
| SCHEMBL10186448 | 0.86 | FAAH (0.47) | FFAR4HRH3KMT2AEPHX2 | |
| SCHEMBL10186181 | 0.84 | DGAT1 (0.47) | DRD4 | |
| SCHEMBL10185477 | 0.84 | CCR3 (0.42) | CCR3HRH3UTS2RHPGDLMNA | |
| SCHEMBL10185480 | 0.84 | CCR3 (0.42) | CCR3HRH3UTS2RHPGDLMNA | |
| SCHEMBL13117660 | 0.82 | CCR3 (0.42) | CCR3HRH3UTS2RPOLBKMT2A | |
| SCHEMBL660935 | 0.82 | DGAT1 (0.55) | KMT2AACSL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | FFAR4 1053/4885CCR3 4296/4885HRH3 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.