Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186448 | 1.00 | FAAH (0.47) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10184281 | 0.88 | KDM4E (0.47) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10185038 | 0.88 | KDM4E (0.47) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10185421 | 0.87 | DGAT1 (0.50) | ALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL10186290 | 0.86 | FFAR4 (0.46) | EPHX2KMT2AHRH3FFAR4 | |
| SCHEMBL663535 | 0.85 | DGAT1 (0.49) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL663534 | 0.85 | DGAT1 (0.49) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10186133 | 0.85 | DGAT1 (0.49) | FAAHEPHX2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL660935 | 0.84 | DGAT1 (0.55) | ALDH1A1MEN1KMT2ARAB9ACYP1A2 | |
| SCHEMBL660936 | 0.84 | DGAT1 (0.55) | ALDH1A1MEN1KMT2ARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | FAAH 1026/4885EPHX2 1718/4885ALDH1A1 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.