Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178369 | 0.90 | PDE4A (0.50) | KDM4EMAPTGAATSHRALDH1A1 | |
| SCHEMBL13761018 | 0.84 | ESR1 (0.47) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL16378277 | 0.81 | CYP1A2 (0.44) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL13513329 | 0.81 | HTT (0.49) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL13513347 | 0.81 | ALDH1A1 (0.45) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL12801465 | 0.81 | KDM1A (0.50) | KDM4EMAPTGAAMEN1KMT2A | |
| SCHEMBL13368603 | 0.77 | FDPS (0.41) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL13390260 | 0.77 | RXRA (0.50) | MAPTS1PR1LMNAL3MBTL1CYP1A2 | |
| SCHEMBL1778039 | 0.76 | HSD17B10 (0.65) | KDM4EMAPTGAAS1PR1MEN1 | |
| SCHEMBL805356 | 0.74 | MAPT (0.61) | KDM4EMAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |