Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657376 | 0.81 | CCR5 (0.36) | PYCR1ALDH1A1MAPK1LMNA | |
| SCHEMBL14808309 | 0.77 | HRH4 (0.41) | HRH4PYCR1ALDH1A1MAPK1 | |
| SCHEMBL24897639 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4ELMNA | |
| SCHEMBL21396202 | 0.74 | HRH4 (0.39) | HRH4PYCR1ALDH1A1MAPK1LMNA | |
| SCHEMBL29325027 | 0.73 | — | — | |
| SCHEMBL7534914 | 0.71 | TSHR (0.39) | ALDH1A1LMNA | |
| SCHEMBL12486617 | 0.71 | HRH4 (0.43) | HRH4PYCR1ALDH1A1MAPK1KDM4E | |
| SCHEMBL27706443 | 0.71 | PYCR1 (0.40) | HRH4PYCR1ALDH1A1KDM4ELMNA | |
| SCHEMBL382259 | 0.68 | ALDH1A1 (0.45) | HRH4PYCR1ALDH1A1MAPK1KDM4E | |
| SCHEMBL23914136 | 0.68 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |