Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197878 | 0.89 | CA12 (0.45) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL28596143 | 0.88 | ALDH1A1 (0.46) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL15897489 | 0.88 | ACACB (0.44) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL1045763 | 0.88 | MEN1 (0.58) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL5738119 | 0.88 | OPRM1 (0.49) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL3550938 | 0.83 | ACACB (0.43) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL31432963 | 0.83 | HRH2 (0.42) | OPRM1SMN1; SMN2ACACBKMT2AMEN1 | |
| SCHEMBL1586829 | 0.82 | L3MBTL1 (0.49) | SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL14447010 | 0.81 | MAP4K4 (0.42) | SMN1; SMN2KMT2AMEN1LMNACTSK | |
| SCHEMBL28594379 | 0.78 | ELANE (0.49) | OPRM1SMN1; SMN2KMT2AMEN1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |