Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594379 | 0.90 | ELANE (0.49) | ALDH1A1LMNAOPRM1HPGDRAB9A | |
| SCHEMBL28603385 | 0.89 | KMT2A (0.49) | ALDH1A1LMNASRD5A2HPGDRAB9A | |
| SCHEMBL28593736 | 0.89 | HRH2 (0.50) | ALDH1A1LMNAOPRM1HPGDKMT2A | |
| SCHEMBL28591389 | 0.89 | KMT2A (0.50) | ALDH1A1LMNAOPRM1HPGDKMT2A | |
| SCHEMBL10188237 | 0.88 | OPRM1 (0.47) | ALDH1A1LMNAOPRM1KMT2AMEN1 | |
| SCHEMBL28605216 | 0.85 | SRD5A2 (0.43) | SRD5A2HPGDRAB9AKMT2ANPSR1 | |
| SCHEMBL28602999 | 0.85 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDRAB9AKMT2A | |
| SCHEMBL28588033 | 0.85 | LMNA (0.48) | ALDH1A1LMNASRD5A2HPGDRAB9A | |
| SCHEMBL28602998 | 0.84 | MAPT (0.45) | ALDH1A1LMNAHPGDKMT2ANPSR1 | |
| SCHEMBL28593739 | 0.84 | OPRM1 (0.45) | ALDH1A1LMNAOPRM1SRD5A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |