Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10189663 | 0.87 | FASN (0.36) | — | |
| SCHEMBL13163368 | 0.69 | DGAT1 (0.49) | DGAT1SOAT1CHEK2HRH4 | |
| SCHEMBL10189573 | 0.68 | DGAT1 (0.55) | DGAT1SOAT1CHEK2 | |
| SCHEMBL901150 | 0.66 | DGAT1 (0.53) | DGAT1SOAT1KCNH2 | |
| SCHEMBL10380302 | 0.65 | HTR3E (0.46) | CHEK2HRH4 | |
| SCHEMBL10188663 | 0.65 | CYP2C9 (0.44) | DGAT1CHEK2 | |
| SCHEMBL10188661 | 0.65 | DGAT1 (0.46) | DGAT1SOAT1KCNH2 | |
| SCHEMBL901616 | 0.65 | DGAT1 (0.46) | DGAT1SOAT1CHEK2 | |
| SCHEMBL7516682 | 0.63 | RHEB (0.51) | DGAT1SOAT1CHEK2 | |
| SCHEMBL10189566 | 0.62 | DGAT1 (0.77) | DGAT1SOAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |