Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31289497 | 0.83 | MEN1 (0.52) | RAF1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL9032997 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL31289470 | 0.82 | MEN1 (0.54) | DGAT1SOAT1RAF1ALDH1A1HPGD | |
| SCHEMBL13163368 | 0.81 | DGAT1 (0.49) | DGAT1SOAT1ALDH1A1HPGDKDM4E | |
| SCHEMBL3335014 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL902206 | 0.79 | DGAT1 (0.61) | DGAT1SOAT1NPC1RIPK1 | |
| SCHEMBL15245092 | 0.78 | KDM4E (0.71) | DGAT1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL22955330 | 0.78 | KDM4E (0.71) | DGAT1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL27741588 | 0.76 | NPC1 (0.56) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL13163367 | 0.76 | PARP1 (0.48) | DGAT1SOAT1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |