SCHEMBL101905

SCHEMBL101905

C=CC(=O)Oc1ccc(-c2ccc(CCCCCCCCCC)cc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 11/20 0.89
THRA P10827 9/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
RARB P10826 8/20 0.56
RARA P10276 2/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPT P10636 1/20 0.56
MTOR P42345 1/20 0.56
RARG P13631 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12193436 0.99 THRB (0.91) THRBTHRAMEN1KMT2ARARB
SCHEMBL28432245 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL6931228 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL10651481 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL187096 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL4475071 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL28428730 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL2289080 0.96 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL823056 0.94 THRB (0.83) THRBTHRAMEN1KMT2ARARB
SCHEMBL11031162 0.94 THRB (1.00) THRBTHRAMEN1KMT2ARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989317-B Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, and polarizing plate 日本瑞翁株式会社 2023-12-01 CN disclosed
CN-110382471-B Polymerizable compound, polymerizable liquid crystal mixture, polymer, optical film, optically anisotropic body, polarizing plate, display device, antireflection film, and compound 日本瑞翁株式会社 2023-09-01 CN disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-11492552-B2 Polymerizable liquid crystal material, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, polarizing plate, anti-reflection film, display device, and method of producing polymerizable liquid crystal composition ZEON CORPORATION (JP) 2022-11-08 US disclosed
CN-111095050-B Polymerizable liquid crystal material, composition, polymer, film, anisotropic body, polarizing plate, device, and method for producing composition 日本瑞翁株式会社 2022-06-07 CN disclosed
EP-3674757-B1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION ZEON CORP (JP) 2022-04-20 EP disclosed
CN-110392703-B Polymerizable compound and method for producing same, polymerizable composition, polymer, optical film, and optically anisotropic body 日本瑞翁株式会社 2022-02-01 CN disclosed
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film ZEON CORPORATION (JP) 2021-12-21 US disclosed
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2021-08-17 US disclosed
US-20120202084-A1 HEAT-INSULATING PARTICULATE PIGMENT AND INFRARED-REFLECTIVE COATING SOLUTION ZEON CORPORATION (JP) 2012-08-09 US disclosed
US-8168734-B2 Lateral alpha-substituted acrylate compound and polymer thereof JNC CORPORATION (JP) 2012-05-01 US disclosed
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-20110144293-A1 LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF CHISSO CORPORATION (JP) 2011-06-16 US disclosed
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS ZEON CORPORATION (JP) 2011-06-16 US disclosed
EP-2295477-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTAL POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS Zeon Corporation (JP) 2011-03-16 EP disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed
EP-2143710-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORPORATION (JP) 2010-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PDE8A, MAPT, PLK4 THRB 4744/4885THRA 4548/4885MEN1 1191/4885
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS CCNB1, CCNT1, CCNB2 THRB 4128/4885THRA 3759/4885MEN1 876/4885
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 THRB 4283/4885THRA 4059/4885MEN1 2693/4885
US-20110144293-A1 LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF LEF1, AFF1, CNKSR1 THRB 1814/4885THRA 958/4885MEN1 771/4885
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film NR2E3, NR3C2, NR2C2 THRB 2007/4885THRA 1913/4885MEN1 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.