Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.97 |
| ▸ | THRA | P10827 | 11/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187096 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL28428730 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL6931228 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL2289080 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL10651481 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL28432245 | 1.00 | THRB (0.97) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL11031162 | 0.98 | THRB (1.00) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL101905 | 0.96 | THRB (0.89) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL12193436 | 0.94 | THRB (0.91) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL1401854 | 0.94 | THRB (0.91) | THRBTHRAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049923-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | Advanced Vision Science, Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008013950-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | ADVANCED VISION SCIENCE, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-20070010883-A1 | Water plasticized high refractive index polymer for ophthalmic applications | ADVANCED VISION SCIENCE, INC. | 2007-01-11 | — | — | US | claimed |
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240309155-A1 | Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-09-19 | — | — | US | disclosed |
| EP-4267708-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | Infineum International Limited (GB) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022136384-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INTERNATIONAL LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| US-8247511-B2 | Water plasticized high refractive index polymer for ophthalmic applications | ADVANCED VISION SCIENCE, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-7563917-B2 | Silicon compound and a production process for silicon compound | CHISSO CORPORATION (JP) | 2009-07-21 | — | — | US | disclosed |
| EP-2049923-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | Advanced Vision Science, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008013950-A2 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | ADVANCED VISION SCIENCE, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20070010883-A1 | Water plasticized high refractive index polymer for ophthalmic applications | ADVANCED VISION SCIENCE, INC. | 2007-01-11 | — | — | US | disclosed |
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | JNC CORPORATION (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004932-A1 | Silicon compound and a production process for silicon compound | STS, SMS, SRM | THRB 1505/4885THRA 822/4885MEN1 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.