SCHEMBL823056

SCHEMBL823056

C=CC(=O)Oc1ccc(-c2ccc(CCCC)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 11/20 0.83
THRA P10827 8/20 0.56
RARB P10826 6/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.48
RARA P10276 1/20 0.48
MAPT P10636 1/20 0.48
MTOR P42345 1/20 0.48
HPGD P15428 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12193436 0.95 THRB (0.91) THRBTHRARARBMEN1KMT2A
SCHEMBL1401854 0.95 THRB (0.91) THRBTHRARARBMEN1KMT2A
SCHEMBL101905 0.94 THRB (0.89) THRBTHRARARBMEN1KMT2A
SCHEMBL11031162 0.91 THRB (1.00) THRBTHRARARBMEN1KMT2A
SCHEMBL815739 0.91 THRB (0.90) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL19456765 0.91 THRB (0.77) THRBTHRARARBMEN1KMT2A
SCHEMBL6931228 0.89 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL187096 0.89 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL2289080 0.89 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL4475071 0.89 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8057701-B2 Trifunctional (meth)acrylate compound and polymerizable composition containing same ADEKA CORPORATION (JP) 2011-11-15 US disclosed
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2011-02-17 US disclosed
US-20070238026-A1 Holographic recording composition, optical recording medium and optical recording method FUJIFILM CORPORATION (JP) 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME PYM1, MT-CO1, MAT1A THRB 341/4885THRA 426/4885RARB 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.